The Effect of Surfactant on the Dissolution Rate of Ibuprofen Tablets

نویسندگان

  • Nighat Razvi
  • Saeed Ahmad Siddiqui
  • Lubna Ghazal Khan
چکیده

The present work was conducted on the effect of surfactant on the dissolution rate of ibuprofen tablets. The cationic (Cetyl Trimethyl bromide) and anionic (Sodium dodecyl sulphate) surfactant present in the dissolution media have remarkable effect on the dissolution rate of Ibuprofen. Maximum dissolution was obtained in the presence of anionic surfactant (Sodium dodecyl sulphate) at 0.5% concentration of deionized water whereas non-ionic (Tween-80) surfactant had little effect on the dissolution of Ibuprofen tablets.

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تاریخ انتشار 2011